Coluracetam powder vs Noopept powder: Which is Better Nootropic?

Coluracetam is a racetam that affects acetylcholine, indirectly. Coluracetam is a high affinity choline uptake enhancer. This activity of the drug increases the efficiency of cholinergic neurons. Most drugs used to treat Alzheimer’s increase acetylcholine, because this neurotransmitter is tightly linked to learning and memory.

coluracetam-chemical-structure
Coluracetam Chemical Structure

Noopept is not technically a racetam, but it behaves like a more potent version of Piracetam. Noopept is best known for its propensity to increase brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). Noopept is also neuroprotective (it protects the brain) in different situations like concussion.

noopept-powder-chemical-structure
Noopept Chemical Structure

One similarity between Coluracetam vs Noopept is that both nootropics are biologically active in minuscule quantities. A typical dose of Noopept is 10-30mg, whereas the standard dose for Coluracetam is anywhere from 3-30mg.

Coluracetam vs Noopept Comparison Table

Coluracetam Noopept
Price 50gram … $500 1 kg … $500
Dosage 3-30mg 10-30mg
Mechanism High affinity choline uptake (HACU) enhancer Similar mechanism to Piracetam; NMDA receptors, and EEG patterns are affected
Effects (anecdotal) Improved mood, working memory and HD vision A mild cognitive boost with subtle psychostimulation
Most similar to Pramiracetam (also a HACU enhancer) Piracetam
Perks Many people’s favorite nootropic, but little evidence to back up the claim that Coluracetam improves cognition Cost-effective, neuroprotective against different neurological insults, a more potent (and potentially better) version of Piracetam

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