Curcumin – Turmeric extract powder

Curcumin ,Turmeric extract powder,  Diferuloylmethane , bright yellow powder

Also Known As

Turmeric extract, Curry Extract, Curcuma, Diferuloylmethane, JiangHuang, Curcuma Longa, 1, 7-bis-{3-methoxy-4-hydroxyphenyl}-1, 6-heptadiene-3, 5-dione

  • CAS Number: 458-37-7
  • Chemical formula: C21H20O6
  • Molar mass:368.39 g/mol
  • Appearance: Bright yellow-orange powder
  • Melting point: 183 °C
  • Usage: Curcumin (diferuloylmethane) is used as an herbal supplement, cosmetics ingredient, food additive, food flavoring and food coloring.

Curcumin Introduction

Curcumin (diferuloylmethane) is a bright yellow powder from turmeric and Ginger. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family (Zingiberaceae). It is sold as an herbal supplement, cosmetics ingredient, food additive, food flavoring and food coloring. Chemically, curcumin is a diarylheptanoid, belonging to the group of curcuminoids, which are natural phenols responsible for turmeric’s’ yellow color. It is a tautomeric compound existing in enolic form in organic solvents and as a keto form in water.
Curcumin is the yellow pigment associated with the curry spice, Turmeric, and to a lesser extent Ginger. It is a small molecule that is the prototypical ‘curcuminoid’, and has effects similar to other polyphenols but unique in a way as it is a different class of polyphenol.

Curcumin Applications

Food additive/supplement

The most common application of Curcumin are as a dietary supplement, in cosmetics, as a food coloring and as flavoring for foods such as turmeric-flavored beverages

Physiological activity

Flavonoid derived from Curcuma longa plant. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC50 values are 8 and 52 μM, respectively). Blood-brain barrier permeable. Shows diverse range of actions including free radical scavenging activity in vitro and in vivo, cardio and neuroprotective effects.

Recommended dosage

For any systemic purpose (requiring absorption from the intestines), then an oral supplementation of curcumin in the range of 80-500mg would be required assuming an enhancement. Curcumin is poorly absorbed inherently, and one of the following is mandatory:

  1. Pairing curcumin with Black Pepper (piperine)
  2. Curcumin phytosomes complexed with Phosphatidylcholine (Meriva or BCM-95)
    Curcumin nanoparticles (THERACURMIN)
  3. Water-soluble curcumin (polyvinyl pyrrolidone)
  4. If one of the above enhancements are not used, then too little curcumin will be absorbed and even doses of up to 4,000mg may be wholly inactive (8-16g would only be slightly active).

If using curcumin for intestinal purposes, then absorption from the intestines into the blood is not necessarily required. Due to this, one can simply use Turmeric at the dose of 2-4g daily or take curcumin supplementation without any of the aforementioned enhancements.

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