Nootropic Powder Oxiacetam

Oxiacetam Chemical Information:

  • Also Known As: 4-hydroxy-2-oxo-pyrrolidinoacetamide, ISF-2522
  • CAS Number: 62613-82-5
  • Appearance:Powder
  • Chemical Names:(RS)-2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
  • Molecular Formula: C6H10N2O3
  • Molecular Weight:158.155 g/mol

Oxiacetam Other names:

  • 4-hydroxy-2-oxo-pyrrolidinoacetamide
  • Hydroxypiracetam

Oxiacetam Chemical Structure:

Oxiacetam Chemical Structure

Oxiacetam Dosage

Supplementation of Oxiracetam tends to be in the dosage range of 1,200-2,400mg taken over the course of a day, either in two to three evenly spread dosing periods (such as three doses of 400mg or 800mg).

Oxiacetam Decription

Oxiracetam is one of the three first-tier Racetam compounds, being produced after both Piracetam and Aniracetam. As a nootropic drug of the racetam family and very mild stimulant, oxiracetam appears to enhance the release of excitatory neurotransmitters and can aid in memory formation.
Oxiracetam is one of the Racetam, and is structurally different from Piracetam due to a single hydroxyl group. It is also used for Nootropic purposes such as enhancing learning in students or preventing against cognitive decline. Like all other racetams, it is a synthetic molecule that is not found in food sources or in nature.

Racetam family

  • Aniracetam
  • Piracetam
  • Phenylpiracetam
  • Others

When looking at the evidence for oxiracetam at this point in time it seems to have a fair bit of human evidence for reducing the rate of organic cognitive decline (a natural loss in cognition that occurs during the aging process that is not associated with any disease state) and with dementia, yet the lone study in persons with Alzheimer’s showed no apparent benefit with oxiracetam supplementation. When it does aid in cognitive decline, it is somewhat comparable in potency to Alpha-GPC and seems to be slightly more potent than piracetam.
Oxiracetam is a positive AMPA modulator similar in mechanism and potency (but not binding site) to both piracetam and Aniracetam but may have an additional benefit of increasing glutamate, acetylcholine, and D-Aspartic Acid release from activated but not resting neurons. This two-fold sequence (enhancing glutamate release and then positively modulating one of the receptors it signals through) ultimately increases metabolic activity in neuronal cells and memory formation.
Oxiracetam has been shown to stimulate receptors in the brain, notably AMPA and NDMA receptors. The compound influences cholinergic systems in the brain, which makes choline an important micronutrient to pair with Oxiracetam. Since Oxiracetam doesn’t have a notable effect on mood in the way some other nootropic compounds do, it is considered a true cognitive booster–it’s taken purely for cognitive enhancement.


  • Increase in Memory
  • Enhanced Learning Ability
  • Better Sensory Perception
  • Advance Technical Thinking
  • Improved Focus

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